I got a screw in the side of my race tires once. With race tires being as expensive as they are I just patched it myself with a murray's patching kit. The screw was about half inch from the edge of the tire, I had no problems with it. I also got screw in on of my street tires, I just ran the screw all the way in and rode it for another 3000 miles. The head made like a seal.