I've had the tb synched but I've never done it myself. I owned an '01 GSXR1000 and had a Yosh pipe,bmc filter,Yosh power commander(can't remember the name of it), and a T.R.E.. The pipe eliminated the exhaust valve and I think that lowered the hp/torque numbers (in the mid range)which resulted in a lessening of the mid range "hit" making the bike easier to ride. It's the same thing I did to my '06. My '03 on the other hand was smooth to begin with,so I just got a slip=on for noise and let it alone otherwise. It was cool that the bike would wheelie at 100 in third gear but it got alittle scary when it wasn't by design!!!